Cheney has gone 100% orange man bad in a state that was 70% orange man great - not a winning bet. She is about as popular in WY as former President Ashraf Ghani is with the Taliban - he fled, I expect her to eventually do the same.
Cheney says she's a candidate for reelection but we'll only know for sure after the deadline for filing has passed. My guess is she's decided to make DC her permanent home and work for some Neo-con Bushie think tank. I can imagine Biden appointing her to some advisory boards and falsely claiming bipartisanship.
If she runs and the state repudiates her, as I expect it will, do you suppose her dad - former Vice President Dick Cheney - will move out of state? He currently lives in a Jackson suburb in appropriately enough the only Democratic county in Wyoming.