After whining about what an asshat Syria's President Bashar Hafez al-Assad is, and how he should abdicate, it looks like the U.S. government will have to eat crow and collaborate with him in opposition to the Islamic State. The U.S. may also have to collaborate with Great Satan-hating Iran to the same end.
There is plenty of precedent for such collaboration. We partnered with the Soviet Union during World War II to stop the Nazis, although we were opponents both before and after the war.
Compared to the Islamic State, Assad's pre-civil war Syria was relatively benign, no threat to the U.S. and not much threat to Israel. At most it menaced Lebanon, only a big deal to the Lebanese.