Writing at The Federalist, Tristan Justice looks carefully at the separatist movement in Eastern Oregon and Northern California. Several rural counties in each state would like to secede and join Idaho, a reliably rural and Republican jurisdiction.
These counties have a legitimate complaint; in each case the values they hold and the people they represent are ignored, if not abhorred, by the dominant Democrats in their respective state capitals. The article makes an interesting point about conservative counties not bothering to enforce state laws of which their populace does not approve. One wonders how far this sort of "cafeteria enforcement" can go before a confrontation occurs.
I know this to be a legitimate issue, the rural CA county I called home for three decades reliably elected Republicans to represent it in Sacramento and DC. Much of the time it did no good, especially in Sacramento. It probably did harm when the state government divvied up resources, I doubt we got our share of the revenue.